Anti-MUC5AC Antibody

货号:BM0054
应用:WB, IHC-P, ICC
反应性:Human,Rabbit,Rat
克隆性:单克隆抗体
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BM0054-100ul 100ul EA ¥1780.00 请登录 请登录
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产品概况

货号BM0054
产品名称Anti-MUC5AC Antibody
基因名MUC5AC
抗体来源Mouse
克隆Monoclonal (Clone: 45M1)
抗体亚型Mouse IgG1
分子量586KD
免疫原Mucin from human ovarian cyst fluid.
内容200ug/ml antibody with PBS ,0.02% NaN3 , 1mg BSA and 50% glycerol.
纯化方式Ascites
浓度200ug/ml
产品形态Liquid
保存条件12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料Mucin 5AC (Muc5AC) is a protein that in humans is encoded by the MUC5AC gene. Using real-time RT-PCR, Moehle et al. (2006) found that MUC5AC was highly expressed in adult trachea and stomach. Expression was lower in adult lung and weak in fetal lung, and no expression was detected in other tissues. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to°Chronic obstructive pulmonary disease. Moreover, Muc5ac is identified as a direct and°Critical mediator of resistance during intestinal nematode infection.
研究类别1. Hasnain, S. Z., Evans, C. M., Roy, M., Gallagher, A. L., Kindrachuk, K. N., Barron, L., Dickey, B. F., Wilson, M. S., Wynn, T. A., Grencis, R. K., Thornton, D. J. Muc5ac: a critical component mediating the rejection of enteric nematodes. J. Exp. Med. 208: 893-900, 2011. 2. Moehle, C., Ackermann, N., Langmann, T., Aslanidis, C., Kel, A., Kel-Margoulis, O., Schmitz-Madry, A., Zahn, A., Stremmel, W., Schmitz, G. Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease. J. Molec. Med. 84: 1055-1066, 2006.
Uniprot IDMUC5AC: P98088
推荐配套的二抗和检测试剂Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and ICC.

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[list_product_images]IHC(P): Human Gastric Cancer Tissue[/list_product_images]
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